OSU Laboratory Discovers New Canine Parvovirus

Here is a press release from the Oklahoma State University Center for Veterinary Health Sciences:

A team of Oklahoma State University (OSU) veterinarians, virologists and pathologists at the Oklahoma Animal Disease Diagnostic Laboratory (OADDL) recently published a paper in the Journal of Clinical Microbiology on their findings from a Canine parvovirus (CPV) study. Led by Dr. Sanjay Kapil, the group is the first to describe the CPV type 2c variant in the United States.

“We were quite fortunate to discover this variant,” explains Kapil. “It has been known for six years in Italy but nobody paid attention to it here until we found it last year.”

Shortly after Kapil joined the OSU Center for Veterinary Health Sciences, he received a case at the OADDL. The adult dog had been vaccinated multiple times and still became sick with Parvovirus.

“This was very unusual and we were totally surprised that it was CPV type 2c, which had not been found in the U.S. until then,” says Kapil. “What was so interesting was that after we described this disease, we ended up with samples from other locations here in the U.S.”

A patent has been filed on the characteristics of the U.S. CPV-2c. The team reports that 500 samples were submitted from locations in south California to south Florida. The published paper has been presented at national level meetings and internationally in Italy and Melbourne, Australia. However, their work is not done.

“The team work was most important. Sometimes we received ten dead puppies a day. We are working with several veterinarians and are receiving samples from cases with a history of vaccine failure,” continues Kapil. “Diagnostic laboratories need to be involved to identify CPV-2c. The disease now exists in all countries except Australia because of its geographical isolation.”

According to Kapil, the disease presentation is different in that normally parvovirus does not affect adult dogs only puppies. However, since publishing their findings, the OADDL has received samples from adult dogs in Minnesota.

“Veterinarians are confused because the in office diagnostic tests come up negative,” explains Kapil. “Clinically it looks like parvovirus so they send it to us. The OADDL tests it and it is parvovirus. Now world-wide (except for Australia), this particular variant can attack the heart and intestines.”

He goes on to say that the mortality has been quite heavy. One breeder lost 600 puppies in one night. Without further testing, it is not known if the cause was simply this virus or if other factors were involved.

“We will continue to study CPV-2c. Through collaborations with others we will search for more effective vaccines,” he promises.

Of 80 cases tested by the OADDL, 26 were from Oklahoma puppies/dogs. Of those 26, 15 tested positive for CPV-2c.

Source: OSU

(Thanks jeff6542)

24 Responses to “OSU Laboratory Discovers New Canine Parvovirus”

  1. Nora and Rufus says:

    600 puppies in one night. HOW in the HELL do you care for 600 puppies????? PUPPYMILL conditions would contribute to 600 puppies dying in one night, and the spread of this strain 2 would be almost impossible to track when the infected dogs from “breeders” are shipped all over the U.S. to different cities for distribution and sale. Some of those puppies are sold before dying and then spread the parvo to the general dog population, not to mention that Parvo is so deadly and easily spread that is can be carried on the bottom of a persons shoes if they step where an infected dog has urinated, vomited or deficated in the last 6 months..That could be any public place, walking or hiking trail, or dog park. THIS IS SCARY.

  2. Judy says:

    That is just what I was thinking too would a reputable breeder have 600 puppies at one time?

  3. Bill says:

    One correction to your comment - the mode of transmission is through ingestion of infected feces. The virus is not airborne nor is it in the urine. It is theoretically possible in vomit since it is an intestinal disease.
    This is straight from the American Veterinary Medical Association.

  4. Nora and Rufus says:

    THIS SHOULD BE REASON ENOUGH TO SHUT DOWN ALL PUPPY MILLS. They have gotten large, wreckless and careless enough to pose a danger to the lives of all the worlds pet population. This is our warning, we must heed it. Oklahoma is one of the leading states of puppy mills…..I am sure there have been many deaths of this Strain2 that have not been reported or were misdiagnosed after the tests came up negative. I cannot put into words how alarming this news is. Also some the innoculations have to be in question….were they up to par, or from China….My vet 2 summers ago informed me at that time there were dogs who had been innoculated and were still coming down with PARVO. I have a feeling that this has been going on longer than we have been made aware of!

  5. Nora and Rufus says:

    Bill, if you feel safe about that, go ahead. We all know that the Veterinary Medical Association is ever changing as they learn also from each new disease. I also did not say it was airborne. Birds can carry it too, for instance if you have a bird feeder and the birds in the neighborhood are flying from yard to yard feeding, they can carry it from one yard to another. THAT INFO CAME FROM THE SAME VET.

  6. Janet and her doggies says:

    So basicly,the shots we are giving our dogs,are not safe guarding them completely.
    what more can we do then….

  7. mittens says:

    large populations contained in small areas with access to each other’s secretions is the ideal vector for disease- it’s the optimal vector actually. that’s why kennels and puppy mills and even , for humans, places like schools have such problems containing and controlling any illness, minor or serious.

  8. kaefamily says:

    “large populations contained in small areas with access to each other’s secretions is the ideal vector for disease- it’s the optimal vector actually. that’s why kennels and puppy mills and even , for humans, places like schools have such problems containing and controlling any illness, minor or serious.”

    I can definitely attest to that … I get sick every year for the past three years at this time since I start working at a pre-K daycare center :-(

  9. clyde behrens says:

    Years ago I purchased a birddog pup borned in a cellar in Morrison OK. approx 20 miles NORTH of Stillwater, Okla.Puppy died, Was told the death was because of the damp enviorment of the cellar.Seems like Parvo was mentioned This had to be in late 60’s or early 70’s. Sad it took so long to find cause.

    .

  10. Maggie says:

    What the #$%^ does this mean ?

    “A patent has been filed on the characteristics of the U.S. CPV-2c. ”

    Why patent the virus ?

  11. cat lady says:

    >

    so they can patent the cure (vaccine) and make all the money of course

  12. G in INdiana says:

    Maggie, same thing as with Indonesia wanting to keep control of the bird flu virus. That way the only samples can be obtained from them for vaccine production and they get cash for providing them.
    Medicine for profit, ain’t it great!

  13. Lis says:

    The current vacine protects quite well against the “new” variant:
    A Canine Parvovirus Type 2 Vaccine Protects Dogs Following Challenge with a Recent Type 2C Strain
    http://www.vin.com/proceedings.....;O=Generic
    That’s from the proceedings of the 2006 World Small Animal Veterinary Congress; this strain has been known in Europe for years, and has probably been in the US for a while, too.

    What’s different about this variant is not that the vaccine isn’t effective against it, and not that adult dogs can get it, too (they can get older strains of parvo, too, but incidence is much lower than in puppies because adult dogs are easier to vaccinate effectively), but that that virus has characteristics that make it harder to diagnose with the currently standard tests. Vets need to be aware it’s out there; pet owners don’t need to be panicking. The money quote here, that explains the loaded language in the press release, is that they’ve patented the virus. They’ll now develop a clinically practical test for it, and patent that, too.

  14. Nancy says:

    Don’t guess ANY of YOU have thought about the fact that the “BREEDER” with 600 puppies got it from SOMEWHERE ELSE. Parvo didn’t miraculously occur in his kennel because he had 600 puppies. It is a virus and can be transmitted on clothes, shoes, picked up in dog parks, and YES even the VETS office and boarding kennels.
    Shame on you all for judging somebody that you don’t even have the faintest idea of what his kennel is like.

  15. cany says:

    Does anyone have an actual COPY of the journal paper? I did go to the source (the author).

    The problem herein for me has been that people that have talked to their veterinarians about this have commented thusly: (paraphrasing here…) that when reading the article surmised it was a hoax given the statement on 600 puppies dying (read puppymill, but most vets don’t get puppymills to begin with…). Not good coming from vets.

    I would like to take the journal article to our rescue veterinarians myself. then have a discussion with them about it. Thus the request for the j. article, itself.

    My advice: Don’t EVER trust your veterinarian. They cannot know every nuance of everything, all the time, from everywhere. It’s our responsibility to be good advocates.

  16. SH says:

    Never hurts to be too educated in these cases. Here’s a good link to help further understand what is going on:
    http://www.petconnection.com/b...../08/parvo/

  17. Anonymous says:

    There’s also this- I haven’t seen much coverage. Due to the symptoms one possibility is a combination of bacterial and equine virus.

    http://www.miamiherald.com/new.....11185.html

  18. Anonymous says:

    @ Nancy: Regardless of the origin of the virus, the point is that one breeder had 600 puppies. That is out of control and thoroughly irresponsible.

  19. don't shop, adopt! says:

    @ Nancy: Regardless of the origin of the virus, the point is that one breeder had 600 puppies. That is out of control and thoroughly irresponsible.

  20. Lisa says:

    Nancy,

    Where the virus came from for that “kennel” is not the issue in the posts you take exception to.

    Anyone with 600 puppies is NOT looking out for the best interests of the dogs. I have three dogs and it is a full-time job giving them all the attention they need and deserve. It would be impossible to give attention and love for 600 puppies, even without the additional adult dogs.

    The fact that the animals died is terrible and sad. I do hope it completely ruined this puppymiller financially so that the mill will never recover and operate. Let’s hope that the person finds a real job to support himself. Puppy milling is blood money.

  21. furrybeasts says:

    Gee, several of my closest and most trusted veterinarians, technicians and caregivers have been trying to convince the staff at OSU that there has been either norovirus or a variant of canine parvovirus around for the past four years right here in Oklahoma. A 100% survival treatment has also been in practice for three out of those four years by sources outside the state by those generous enough to share their findings. Now that the embarassment of denial is too great, suddenly it’s OSU who has discovered the new strain, and still no indication of how to treat it. I guess that will be their discovery as well. I know where the real credit lies. I have discussed this myself with OSU staff with no results. Oh, by the way, OSU also researched Cytauxzoon felis in 2000-2002 and determined there was no cure. I can attest that our same researcher has been curing C. felis for over four years and I have cured my own with this protocol, only to be told by OSU that “We have a different, more virulent strain here.” I guess OSU’s press release discovering a cure for C. felis will be the next headline. Must be nice to bask in others hard work.

  22. Annette says:

    I have the cure and have been curing this virus strain as well as standard parvo for nearly 4 years. Dr. Jack Broadhurst discovered it, and he owns the patent on THAT!
    I sent 4 bodies to OSU then of dogs who were vaccinated and told them we had a new strain 4 years ago. (under the name Helvey) We were currently treating 38 in one kennel. We saved all of them with our new treatment. Since have saved thousands nation wide in the clinical trial. I have tried and tried to share this info. Tomorrow night at 10 pm on ch 2 is my last attempt, and I give up. I will have to be satisfied with the knowlege and hope the medical world will eventually give a parvo puppy tamiflu and watch it recover before their eyes. I still have hope.
    Email me for treatment info. I wont respond to hate mail. My response is “treat a parvo puppy yourself, discover the miracle or leave me alone” I have nothing to prove. This clinical trial is completed and the results are being compiled. Its done and soon will become protocol, but how many have to die until then.
    Annette
    wheartranch@aol.com

  23. Ann Quinn says:

    Please help us. We only have a few dogs but the pups are dying at about 4-6 weeks. The vets don’t have any idea what to do. I have had horses for years and can certainly treat these puppies if I know what to do. I have had a couple tested with the swab test and they said it was positive for parvo. We did not see any vomiting or nasty stools in these pups. They just became letharagic and in 24 hours were gone. Thanks, for any help you can give us. Ann Quinn

  24. amy fearn says:

    I just got a puppy from an oklahoma puppy “broker” and she tested positive for parvo as well. She didn’t have diarrhea or vomiting until the 4th day. She is in ICU getting a transfusion and iv fluids..they gave us 50 percent chance and this after spending $2000, I kid you not. We may choose to humanely euthanize her tomorrow if no improvement overnight. I told the breeder and do you know she is still selling the litter? Supposedly, they aren’t sick. I am so angry and feel like a fool. My heart is broken for my baby and sick over the lack of rules that protect a buyer.


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